A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction as an underlying fibrotic stimulus
Background & Aims: High-dose irradiation is an essential tool to help control the growth of hepatic tumors, but it can cause radiation-induced liver disease (RILD).This life-threatening complication manifests itself months following radiation therapy and is characterized by fibrosis of the pericentral sinusoids.In this study, we aimed to establ